Evaluasi Penggunaan Obat Anti-Tuberkulosis dan Clinical Outcome Pasien Tuberkulosis Ekstra Paru di Rumah Sakit Paru Dr. M Goenawan Partowidigdo

Nisa Najwa Rokhmah, Dewi Oktavia Gunawan, Whidya Ningsih

Abstract


Extra-pulmonary tuberculosis is tuberculosis that causes involvement of organs outside the lung parenchyma. Data detected tuberculosis cases in Indonesia were 717,941 cases, about 20-25% of tuberculosis cases occurred outside the lungs. This study was a descriptive analysis with retrospective data collection conducted at RSPG. Data were analyzed by means of descriptive univariate analysis and bivariate analysis using chi-square statistics. The use of anti-tuberculosis drugs in extra-pulmonary tuberculosis patients using first-line treatment, namely: Rifampicin, Isoniazid, Pyrazinamide and Ethambuthol. The results of the Clinical Outcome analysis of 50 patients based on the parameters of clinical symptoms, body weight, BTA test results and Thorax X-rays, namely there were 40 patients (80%) who experienced improvement in clinical symptoms, 42 patients (84%) experienced weight gain, 50 patients (100%) did not experience changes in BTA test results and 36 patients (72%) who experienced improvement in Thorax X-ray examination results. The results of Chi-square analysis showed that there was a significant influence between anti-tuberculosis treatment on Clinical Outcome based on patient clinical symptoms (p<0.05).


Keywords


Extrapulmonary tuberculosis; Anti-tuberculosis drug; Clinical Outcome; Clinical Symptoms; Body Weight

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References


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DOI: https://doi.org/10.31764/lf.v6i1.24712

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