Struktur dan Distribusi Senyawa yang Diisolasi dari Berbagai Bagian Tanama Kadara (Caesalpinia bonduc): Review

safwan safwan, Sucilawaty Ridwan, Abdul Rahman Wahid

Abstract


Kebiul atau Kadara (Caesalpinia bonduc) merupakan tanaman yang tumbuh di daerah yang lebih panas dan telah dimanfaatkan sebagai obat tradisional. Beberapa daerah di Indonesia seperti Bima dan Dompu, tanaman kadara sangat banyak digunakan dalam formulasi obat tradisional seperti obat tradisional penambah nafsu makan. Beberapa laporan menunjukan, tanaman kadara mengandung berbagai senyawa yang memiliki aktivitas biologis. Ulasan penelitian ini melaporkan struktur dan distribusi senyawa yang telah diisolasi dari berbagai bagian dari tanaman kadara. Semua data ulasan diambil dari database Reaxys yang diseleksi berdasarkan kriteria inklusi-eksklusi dengan kata kunci Caesalpinia bonduc, new compound, tanpa batasan waktu. Hasil pengumpulan data diperoleh sebanyak 18 artikel yang sesuai kriteria. Hasil pengolahan data dari 18 artikel yang diperolah, sebanyak 98 struktur senyawa dari 5 bagian tanaman, terdistribusi sebanyak 53 dari daging buah, 13 dari akar, 12 dari barang, 10 dari daun, dan 10 dari kulit biji. Semua senyawa dari bagian daging buah dan akar teridentifikasi sebagai golongan diterpenoid sementara bagian laiinya dari golongan flavonoid, fenilpropanoid, polifenol, dan kuinon. Umumnya senyawa-senyawa tersebut diekstraksi menggunakan metode maserasi dengan melarut metanol atau etanol dan difraksinasi menggunakan pelarut etil asetat, serta diisolasi menggunakan KLT dan HPLC semi-preparatif.

Keywords


Kebiul; Kadara; Caesalpinia bonduc; Senyawa

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References


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DOI: https://doi.org/10.31764/lf.v4i1.13245

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