Analisis Drug Related Problem (DRPs) Pada Pasien Congestive Heart Failure (CHF) di Instalasi Rawat Inap Rumah Sakit X Kota Bandar Lampung

Ni Ketut Anggun Damayanti, Mulan Gevika Amara Putri, Ni Komang Tria Pradnyani Dewi, Ida Bagus Ketut Widnyana Yoga, Tambunan, Matthew Valentino

Abstract


Congestive Heart Failure (CHF) is a condition in which the heart is unable to maintain sufficient cardiac output to meet the oxygen and metabolic demands of body tissues despite adequate venous return. Drug-Related Problems (DRPs) are events or circumstances involving drug therapy that have the potential to interfere with the desired health outcomes. This study aimed to identify the occurrence of DRPs in patients with CHF and to determine the category with the highest percentage of DRP events among CHF patients hospitalized at Hospital X in Bandar Lampung City in 2024. This study employed an observational design with a descriptive cross-sectional approach and retrospective data collection, using medical records from January to December 2024. A total of 51 samples were selected using purposive sampling. The study population consisted of 51 CHF patients, comprising 38 (74.51%) male patients and 13 (25.49%) female patients. The results showed that the incidence of DRPs among CHF patients was relatively high, at 87.93%. The category with the highest proportion of DRP events was drug selection, with 165 events (59.36%). Other categories included treatment effectiveness with 54 events (19.43%), therapy safety with 51 events (18.35%), and dose selection with 8 events (2.88%). In conclusion, the subcategory with the highest percentage of DRP events was the use of medications that were not in accordance with clinical guidelines or the hospital formulary, accounting for 50 events (17.99%).


Keywords


Kadar bahan aktif; Zero Crossing; Persamaan Simultan Sederhana; Variasi Pelarut; Spektrofotometer UV-Visible

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References


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DOI: https://doi.org/10.31764/lf.v7i1.36075

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